Clinical

The Adtec SteriPlas is a topical antimicrobial medical device that has been shown to have a greater microbial load reduction than antibiotics on wounds in RCTs (1) and has efficacy against biofilms (2,3). It has proven efficacy in management of infection in surgical site infections (4,5). Gas plasma is also a broadspectrum antimicrobial (including multi-resistant strains) and with a physical mode of action, resistance is unlikely to be developed (6). The Adtec SteriPlas also has proven efficacy in the treatment of Actinic Keratoses (7).

Wounds

The Adtec SteriPlas is a broad-spectrum antimicrobial that delivers a physical bombardment on bacteria. Acting directly on the surface of the wound it can destroy multi-resistant bacteria present, promoting the accelerated healing of the wound.

 

Diabetic foot ulcers are considered to be the most complex of all leg ulcers which are often non-healing.

  • £7,800 cost per patient for the treatment of  diabetic foot ulcer using standard treatment methods over 12 months. 8
  • £16,900 cost per amputation for diabetic foot ulcer patient over 12 months. 8
  • The Adtec SteriPlas is not only proven to accelerate wound healing but cheaper to operate than those of standard antimicrobial wound treatments.

Surgical site infections

Infected drivelines may show recalcitrance to treatment with antibiotics and antimicrobial dressings. Antimicrobial dressings are unable to wrap the around infected driveline towards the source of biofilm.

Using the Adtec SteriPlas for the treatment of surgical site infections has shown remarkable results in accelerated healing (9,10,11). The gas plasma produced can penetrate through the gaps in crevices around the infected driveline reaching towards the source of biofilm where the bacteria is then destroyed using a physical mode of action.

Dermatology

The Adtec SteriPlas can be used in a wide range of dermatological applications including Actinic Keratoses. It has been tested on patients with Actinic Keratoses to deliver promising results leading to accelerated healing. Although various therapy options do exist, they often bear undesirable side effects7. Throughout the course of its existence, the Adtec SteriPlas has shown to have no side effects which offers patients a novel and safe option to be treated.

The flawless design of the Adtec SteriPlas incorporates a generous 12cm2 treatment area allowing significantly more patches of Actinic Keratoses to be covered during treatment, with no limitations on how many areas can be covered during the appointment.

Alternative therapies may involve patients having a longer wait period between sessions, whereas the Adtec SteriPlas allows repetitive treatments to be applied with no side effects. Adtec recommends at least one application per week using the Adtec SteriPlas.

Case Studies

Bibliography

Plasma therapy – Once a week enough? Prospective RCT to validate the interval of plasma treatment for

reduction of wound area, bacterial load and pain, F. Jockenhöfer, EWMA 2018

 

Actinic keratoses treated with cold atmospheric plasma, M. Wirtz, MDI. Stoffels, MD; J. Dissemond, MD;

D. Schadendorf, MD; A. Roesch, MD, J. Eur. Acad. Dermatol. Venereol. Online July 11, 2017.

 

Remove it or treat it – New technologies for complicated wounds, Rotering H., EWMA 2018 (e-poster)

 

Successful and Safe Use of 2 Min Cold Atmospheric Argon Plasma in Chronic Wounds: Results of a

Randomized Controlled Trial. Isbary, G., J. Heinlin, T. Shimizu, J. L. Zimmermann, G. Morfill, H-U Schmidt,

R. Monetti, B. Steffes, W. Bunk Y. Li, T. Klaempfl, S. Karrer, M. Landthaler and W. Stolz,. British Journal of

Dermatology (2012). 167 (2): p. 404-10.

 

 

1. Isbary BJD 2012 167,404-110 ; 2. Ermolaeva JMM 2011 60,7583 ; 3. Booth Wounds UK, 2015 ; 4. Rotering EWMA Bremen 2016 ;  5. Rotering WUWHS 2016 ; 6. Isbary BJD 2010 163, 78-82 ; 7. Wirtz, JEADV 2017 ; 8. Guest, Int Wound J 2018, 15:43 – 52 ; 9. Rotering, EWMA Bremen 2016 ; 10. Rotering WUWHS 2016 ; 11. Rotering WUWHS 2017

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